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ICE

Guide to use of Material Safety Data Sheets (MSDS)

III. Glossary of common hazard communication terms

Without being exhaustive, this section provides definitions for many common terms used in Material Safety Data Sheets, labels and other documents related to hazard communication.
Absorption Penetration of a substance into another substance.
Acidosis Acid poisoning in the blood.
Acid A chemical which has the ability to neutralise an alkali to form a salt. Certain acids react vigorously with metals, releasing hydrogen gas. Acids may also be corrosive to the skin, eyes and mucous membranes, especially in concentrated form. Acid turns blue litmus paper red. Sulphuric, hydrochloric and nitric acid are common examples.
Acute Effect An adverse effect on a human or animal, following a single dose or short exposure with symptoms developing rapidly.
Acute Toxicity The toxic effects resulting from a single dose or short exposure to a substance.
Adsorption Condensation of gases, liquids or dissolved substances on the surfaces of solids.
ADN/ADNR European regulations for inland waterway transport of hazardous goods.
ADR European regulations for road transport of hazardous goods.
Aerobe Micro-organisms that survive in the presence of oxygen (air).
Aerosol An airborne mist of a solid or liquid substance.
Alcohol Resistant Foam Medium to fight fires of highly flammable, water soluble substances. It has less mechanical strength than other foams.
Aliphatics Refers to an open-chain or fatty series of hydrocarbons. Usually applied to petroleum products derived from a paraffin or olefin base and having a straight or branched chain molecular structure. Substances such as ethane and ethylene are typical aliphatic hydrocarbons. Also see "Aromatic".
Alkali A compound that has the ability to neutralize an acid to form a salt. A substance which is somewhat irritating or corrosive to the skin, eyes and mucous membranes. Turns red litmus paper to blue. Common strong alkalis are sodium and potassium hydroxide.
Allergic Reaction An abnormal physiological response in a person who has become hypersensitive to a specific substance. Some forms of dermatitis and asthma may be caused by allergic reactions to chemicals.
Anaerobe Micro-organisms that survive without oxygen (air).
Anaesthetic Effect The temporary loss of feeling which reduces the ability to feel pain and/or other sensations.
Antidote An agent that neutralizes or counteracts the effects of a poison.
Aromatics The name "aromatics" is derived from their rather pleasant odour. The chemical may, however, be carcinogenic. Refers to petroleum products which have a ring molecular structure. Aromatics tend to burn with black, smoky flames. Benzene, toluene and xylene are the principal aromatics.
Asphyxiant A vapour or gas which can cause unconsciousness or death by suffocation (lack of oxygen).
Aspiration Hazard The danger of drawing a fluid into the lungs and causing chemical pneumonia or other inflammatory response.
ASTM American Society for Testing Materials.
Auto-ignition Temperature The approximate lowest temperature at which a flammable gas or vapour-air mixture will spontaneously ignite without spark or flame.
Bar Unit of pressure.
Normal atmospheric pressure = 1.013 bar (=1013 mbar)
Bioaccumulation The process in and by which chemical substances are accumulated in living organisms.
Biodegradation Natural decomposition of a substance via biological processes.
Boiling Point The temperature at which a liquid changes to a vapour state, at a given pressure. For mixtures, the initial "boiling point" or the "boiling range" may be given.
Burns An injury to skin tissue caused by heat, chemicals, electricity or irradiation.
°C Degrees Celsius or Centigrade.
"CL" The maximum allowable human exposure limit for an airborne substance; not to be exceeded, even momentarily. Also see "PEL" and "TLV".
Carcinogen A substance or agent capable of causing cancer.
C.A.S. Number A number assigned to specific chemicals by the Chemical Abstracts Service. (An organization operated by the American Chemical Society which indexes chemical information).
Caustic A compound that strongly irritates, burns, corrodes or destroys living tissue.
cc Cubic centimetre. A volume measurement in the metric system, equal in capacity to one millilitre (ml).
Chemical Pneumonitis Inflammation of the lungs, caused by inhalation or aspiration of an irritating substance.
Cocarcinogen Material which potentiates the effect of a carcinogen.
COC Cleveland Open Cup: a flash point test method.
Coma A state of deep unconsciousness from which one cannot be aroused, even by powerful stimulation.
Combustible A substance capable of fuelling a fire.
Compatibility Ability of two or more substances to mix without objectionable changes in their physical or chemical properties.
Condensation Change in physical state of a substance from vapour to liquid (or solid) form.
Container Any bag, barrel, bottle, box, can, drum, reaction vessel, storage tank, road- or rail-tanker, or the like that contains a hazardous chemical. Pipes or piping systems are not considered to be containers.
Corneal/Conjunctival Burns Burns to the transparent membrane covering the eyeball and lining of the eyelids.
Corrosive A material that causes visible destruction or irreversible alterations in tissue at the site of contact.
Cutaneous Of or relating to skin.
Decomposition Breakdown of a material or substance (by heat, chemical reaction, electrolysis, decay or other processes).
Defatting The removal of natural oils from the skin by a fat-dissolving solvent.
Deflagration To burn rapidly with intense heat and sparks being given off.
Dehydration The removal of water from a substance. A condition that results from an excessive loss of body fluids. Abnormal depletion of bodily water.
Dermal Of or pertaining to the skin.
Dermal Toxicity Toxic effects resulting from skin exposure to a substance.
Dermal Sensitisation A hypersensitivity response of the skin resulting from repeated contact with an allergenic substance.
Dermatitis Inflammation of the skin often characterised by oozing, redness and itching.
Detonation To explode with sudden force.
Downwind In the direction toward which the wind is blowing in relation to the object or area in question.
Dry Chemical Powder A powdered fire extinguishing agent.
Dusts Solid particles suspended in air generated by a mechanical process such as crushing, grinding, abrasion or blasting.
Epidemiology An allied health science that is concerned with the determination of the specific causes of outbreaks of infection, disease, and health effects.
Eschar A thick crusting or scabbing on the skin.
Explosive A chemical that causes a sudden, almost instantaneous release of pressure, gas and heat when subjected to sudden shock, pressure or high temperature.
Explosive Limits The range of concentration of a flammable gas or vapour (percent by volume in air) in which explosion can occur if an ignition source is present.
Exposure Limit Limit set to minimise occupational exposure to a hazardous substance.
Extinguishing Agents Media suitable for controlling or putting out a fire, when properly applied.
°F Degrees Fahrenheit: T(°C) = [T(°F)-32] x 5/9
Fatal Causing death; deadly.
Fibrosis A condition marked by the abnormal increase in the amount of fibrous connective tissue in an organ or tissue.
Fire Point The lowest temperature at which a material can evolve vapours fast enough to support continuous combustion.
First Degree Burn A mild burn, characterized by pain and reddening of the skin.
Flammable A material which is easily ignited.
Flash Point The minimum temperature at which a liquid gives off sufficient vapour to form an ignitable mixture with air.
Foetal Of or pertaining to a foetus. The unborn young of an animal while still in the uterus.
Freezing Point The temperature at which a liquid substance changes to a solid state.
Frostbite Damage to tissues resulting from exposure to extreme cold or contact with extremely cold liquids or objects.
Frothing Bubbles formed on or in a liquid; foaming.
Fumes Fumes are formed by processes such as sublimation or condensation and is the term generally applied to particles condensed from the gaseous state (e.g. metal fumes, polymer fumes).
Gas May be compressed, liquefied or dissolved under pressure.
Gastric Lavage The irrigation or washing out of the stomach by means of a gastric tube.
Gastrointestinal Disturbances A general term used to describe any symptoms referrable to the stomach or intestines such as nausea, vomiting, cramping and/or diarrhoea.
g/kg Grams per kilogram. An expression of dosage used in toxicology testing, to indicate the grams of substance dosed per kilogram of animal body weight.
Hazard Warning Any words, pictures, symbols, or combination thereof appearing on a label or other appropriate form of warning which convey the hazards of the chemical(s) in the container(s).
Hazardous Chemical Any chemical which is a physical, health or environmental hazard.
Health Hazard A chemical for which there is statistically significant evidence based on at least one study conducted in accordance with established scientific principles that acute or chronic health effects may occur in exposed employees.
Hydrocarbons Compounds composed solely of carbon and hydrogen.
Hygroscopic Capacity to absorb water.
ICAO/IATA International regulations for air transport of hazardous goods.
IMO/IMDG International regulations for maritime transport of hazardous goods.
Ignition Source Anything that provides beat, spark or flame sufficient to cause combustion/explosion.
Impervious Incapable of being penetrated by a substance.
Inhibitor A substance which is added to another substance to prevent an unwanted chemical reaction from occurring.
Irritant A substance which will cause an inflammatory response or reaction of the eye, skin or respiratory system.
LC50 Lethal Concentration 50%; the concentration of a material in air which on the basis of laboratory tests, is expected to cause 50% mortality in a group of test animals when administered as a single exposure.
LD50 Lethal Dose 50%; a single dose of material which, on the basis of laboratory tests, is expected to cause 50% mortality in a group of test animals when administered as a single exposure.
LEL or LFL Lowest Explosive Limit or Lower Flammable Limit.
Melting Point The temperature at which a solid substance changes to a liquid state.
mg/kg Milligrams per kilogram. An expression of toxicological dose.
mg/m³ Milligrams per cubic metre; a unit for measuring concentrations of particulates or gases in the air (a weight per unit volume).
Mist Liquid droplets suspended in the air.
mm Hg Millimetres (mm) of mercury (Hg). Unit of pressure. Normal atmospheric pressure = 760 mm Hg.
Mucous Membrane A thin layer of mucous-secreting tissue covering a body surface or lining an organ. For example : the nose, stomach, intestines and bronchial tubes.
Mutagen A substance or agent capable of altering the genetic material of a living cell.
Nausea An unpleasant sensation, often culminating in vomiting.
Neutralise To render chemically neutral or harmless; neither acid nor base.
Non-combustible A material which will not ignite, burn, support combustion or release flammable vapours when subjected to heat or fire.
N.O.S. Abbreviation for "Not Otherwise Specified". Used as a collective entry in transport regulations to which substances may be assigned if they are not mentioned by name.
Ocular Affecting the eye.
Oedema The presence of abnormally large amounts of fluid in the tissue spaces of the body. May be visible as swelling of a body part such as the legs or face.
Olfactory Relating to the sense of smell.
Oral Affecting the mouth.
Oral LD50 Oral Lethal Dose 50%; the concentration of a substance, orally administrated which will produce 50 percent mortality in the animals tested.
Oral Toxicity Adverse effects which result from taking a substance into the body via the mouth.
Oxidising Agent A chemical other than a blasting agent or explosive that initiates or promotes oxidation in other materials, possibly causing fire either of itself or through the release of oxygen or other gases.
Pa Pascal : unit of pressure.
Normal atmospheric pressure = 101.3 kPa
Paralysis Partial or complete loss of function of a sense (such as smell) or partial or complete loss of motor function of a part of the body.
Partition Coefficient (n-octanol/water) Distribution coefficient used to evaluate the harm the substance can cause to environment. Higher values indicate higher chance of accumulation of the substance in biological material.
Pathological Changes Abnormal structural and/or functional changes in a body caused by a diseased state or exposure to a toxic chemical.
PEL Permissible Exposure Limit. May be a Time Weighted Average (TWA limit) or a "ceiling" concentration exposure limit.
pH Numerical logarithmic scale from 0 to 14 indicating whether a product is acid (pH < 7), alkaline (pH > 7) or neutral (pH = 7)
Physical Hazard A chemical for which there is scientifically valid evidence that it is: a combustible liquid, a compressed gas, explosive, flammable, an organic peroxide, an oxidising agent, pyrophoric, unstable (reactive) or water-reactive substance.
PMCC Pensky Martens Closed Cup : a flash point test method.
Polymer A high molecular weight material formed by chemically joining together five or more molecules (monomers).
Polymerisation A chemical reaction in which a large number of relatively simple molecules combine to form a large chainlike molecule. A hazardous polymerisation is a reaction which takes place at a rate which releases large amounts of energy.
Polynuclear Aromatic Hydrocarbons Organic compounds usually composed of three or more aromatic rings. Some of these compounds (esp. 4-6 ring compounds) are capable of causing skin tumour formation. Also known as PNA's or PAH's.
Pour point The lowest temperature at which a liquid will flow or pour.
ppm Parts per million; a unit for measuring the concentration of a gas or vapour in air,' parts (by volume) of the gas or vapour in a million parts of air. Concentration of a particular substance in a liquid or solid.
ppb Parts per billion : a unit for measuring the concentration of a gas or vapour in air; parts (by volume) of the gas or vapour in a billion parts of air. Also used to indicate the concentration of a particular substance in a solution or solid.
Preparation Intentional mixture or solution composed of two or more substances.
Protective Clothing Clothing designed to provide protection to the wearer against contamination from chemical, biological, radiation or physical hazards.
psi Pounds per square inch. Unit of pressure.
Normal atmospheric pressure = 14.7 psi
Pulmonary Oedema The abnormal accumulation of fluid in the tissue and air spaces of the lungs.
Pyrolysis The breaking apart of complex molecules into simpler units by the use of heat, as in the pyrolysis of heavy oil into gasoline.
Pyrophoric A chemical that will ignite spontaneously in air.
Radioactive The property of an isotope or element which is characterised by giving off radiant energy in particles or rays by the disintegration of atomic nuclei.
Reactivity The tendency of a substance to undergo a chemical change with the release of energy. Undesirable effects (pressure build-up, temperature increase, formation of noxious, toxic or corrosive by-products) may occur because of a reaction to heating, burning, direct contact with other materials or other conditions when in use or in storage.
Reducing Agent The material which is oxidised or which allows easy oxidation.
Respiratory Protection Devices for use in conditions exceeding the exposure levels, which when properly selected, maintained, and operated by the user, will protect the user's respiratory system from exposure to airborne contaminants by inhalation.
Respiratory System The breathing system; includes the lungs and the air passages (trachea or windpipe, larynx, mouth and nose) to the air supply outside the body.
RID European regulations for rail transport of hazardous goods.
R phrases Risk phrases : a set of numbered standard sentences which appear on user labels for packaged goods (e.g. R23 : Toxic by inhalation).
Second Degree Burn A burn that is more severe than a first degree bum, and is often characterized by blistering, reddening of the skin, oedema and destruction of the superficial tissue.
Sensitiser A substance, which on first exposure, causes little or no reaction in man or test animals, but which on subsequent exposure(s) may cause a marked allergic response, not necessarily limited to the contact site. Skin sensitisation is the most common form in the industrial setting, although respiratory sensitisation to a few chemicals has been known to occur.
SETA Setaflash Closed Tester; a flash point test method.
Simple Asphyxiant A substance which induces a deficiency in the supply of oxygen. Nitrogen, methane and acetylene are examples.
Skin Lesion An abnormal change in the structure of the skin due to injury or disease.
Solubility in Water The percentage of a material (by weight) that will dissolve in water at a specified temperature.

negligible or nil

less than 0.1 percent

slight

0.1 to 1.0 percent

moderate

1 to 10 percent

appreciable

more than 10 percent

complete

soluble in all proportions
Solution Uniformly dispersed mixture. All solutions are composed of a solvent (water or other fluid) and the dissolved substance, called the "solute".
Specific Gravity The ratio of the weight of material to be weight of an equal volume of water usually at 20 degrees C, unless otherwise specified. Specific gravity of water = 1.
S phrases Safety phrases : a set of numbered standard sentences which appear on user labels for packaged goods (e.g. S 15: Keep away from heat)
STEL Short Term Exposure Limit (see TLV-STEL).
Substance (chemical) Chemical element and its compound in the natural state or obtained by any production process, including any additive necessary to preserve the stability of the product and any impurity deriving from the process used, but excluding any solvent which may be separated without affecting the stability of the substance or changing its composition.
Symbol Pictogram appearing on user labels for packaged goods, also characterised by a letter (e.g. picture of flame and F+ : very flammable substance).
Symptom Abnormality in the body which is noticeable only to the person experiencing it and may indicate poisoning or disease.
Systemic Toxicity The adverse effects caused by a substance, affecting the body in a general rather than a local manner.
TCC Tag (Tagliabue) Closed Cup : a flash point test method.
Teratogen A substance that upon exposure to the parent causes malformations and/or alterations in the appearance or function of the foetus.
Third Degree Burn The most serious type of bum, is characterized by charring (blackening) of the skin, and skin necrosis (tissue death).
TLV Threshold Limit Value : a term used to express the airborne concentration of a material to which nearly all persons can be exposed day after day, without adverse effects.
TLV-C Ceiling Exposure Limit, the concentration that should not be exceeded, even momentarily.
TLV-STEL Short Term Exposure Limit, or maximum concentration for a continuous 15-minute exposure period (maximum of four such periods per day, with at least 60 minutes between exposure periods, and provided that the daily TLV-TWA is not exceeded).
TLV-Skin (Listed substance followed by the designation "skin"): The skin designation refers to the potential contribution to the overall exposure by the cutaneous route, including mucous membranes and the eye. Exposure can be either by airborne or direct contact with the substance. This "attention calling" designation suggests appropriate measures be taken to prevent skin absorption. The TLV is not invalidated.
TLV-TWA The allowable Time Weighted Average concentration for a normal eight hour workday or 40 hour work week. May also be adjusted for extended work shifts.
TOC Tag (Tagliabue) Open Cup : a flash point test method.
Toxicity Inherent capacity to produce injury. Adverse effects resulting from overexposure to a material, generally via the mouth, skin, eyes or respiratory tract.
Toxicology The study of the key effects of chemicals and or physical agents on living systems, including evaluation of safety.
Transient Short in duration.
Transport Emergency Card (Tremcard) Instructions on how to deal with emergencies involving hazardous chemicals, transported by road.
Tumour Abnormal mass of tissue.
TWA Time Weighted Average exposure: the airborne concentration of a material to which a person is exposed, averaged over the total exposure time, generally the total workaday, (eight to twelve hours). Also see "TLV".
Ulcer A lesion (wound/injury) on the surface of the skin or mucous surface.
Unconscious Not conscious : incapable of responding to sensory stimuli.
Unstable Tending toward decomposition or other unwanted chemical change during normal handling or storage.
Unstable (Reactive) A chemical which in the pure state, or as produced or transported, will vigorously polymerise, decompose, condense, or will become self-reactive under conditions or shocks, pressure or temperature.
UN Number United Nations Substance Identification Number (for transport purposes).
Upper Flammable Limit (UFL) The highest concentration of a flammable vapour or gas in air (usually expressed in percent by volume) above which propagation of a flame will not occur in the presence of an ignition source. Also called upper explosive limit or UEL.
Upwind In the direction from which the wind is blowing. Also see "downwind".
Vapour Density The relative weight of a vapour compared to an equal volume of air (indicates whether vapours will rise or sink).
Vapour Pressure Pressure of saturated vapour above liquids or solids (usually provided at 20°C). The higher the vapour pressure, the higher the concentration will be in unventilated spaces.
Viscous Having resistance to flow.
Water-reactive A chemical that reacts with water to release a gas that is either flammable or presents a health hazard.